Dose       Sample R-1:I-y R-1:I-z R-2:I-y R-2:I-z Label
	          				    
Dose-1.044      S    78.9    79.8    79.0    79.1 ""
Dose-1.321      S   108.2   113.1   119.1   122.5 ""
Dose-1.670      S   176.9   180.1   173.6   169.8 ""
Dose-1.000      T    79.8    76.4    78.9    78.7 ""
Dose-1.265      T   107.2   106.5   117.7   117.3 ""
Dose-1.600      T   168.2   171.4   179.3   162.7 ""

# Model                    . . . . "Parallel lines"
# Design                   . . . . "Completely randomised"
# Transformation           . . . . "y' = log((y+z)/2"
# FUN                      . . . . "function(x) log(apply(array(x, dim = c(6, 2, 2)), c(1, 3), mean))/log(10)"
# INV                      . . . . "function(x) 10^(x)"
# Factor                   . . . . "1044, 104.4, 100 / 0.98653970"
# Rows                     . . . . "Dilutions & Samples"
# Columns                  . . . . "Replicates by pairs"
# DilutionRatio            . . . . "sqrt(sqrt(1.67 * 1.6 / 1.044))"

# ResultOfAssay            . . . . "Example 5: Heparin Sodium"
# Project                  . . . . "CombiStats - EDQM, Council of Europe"
# Description              . . . . "Three-dose parallel line assay; explicit content notation"
# Comment                  . . . . "Custom transformation"
# Resume                   . . . . ""
# Date                     . . . . ""
# Operator                 . . . . ""

# Source                   . . . . "CombiStats - EDQM, Council of Europe"
# URL                      . . . . "http://combistats.edqm.eu/images/stories/Examples/Heparin%20sodium.pdf"
# Example                  . . . . "05"
# Substance                . . . . "Heparin Sodium"
# Method                   . . . . "European Pharmacopoeia (1997), 2.7.5"

# StandardSample           . . . . "Ph. Eur. BRP Batch 1"
# StandardAssPot           . . . . "1044 IU/ml"
# StandardDilutions        . . . . "1.044 1.321 1.670"

# Sample1Sample            . . . . "In-house reference"
# Sample1AssPot            . . . . "1000 IU/ml"
# Sample1Dilutions         . . . . "1.000 1.265 1.600"

# A1@Preparations        1    0.000289614    0.000289614    1.002    0.355
# A1@Regression          1    0.232114       0.232114     803.381    0.000
# A1@Non-parallelism     1    3.01665E-05    3.01665E-05    0.104    0.758
# A1@Non-linearity       2    0.000340714    0.000170357    0.590    0.584
# A1@_Standard           1    9.14836E-05    9.14836E-05    0.317    0.594
# A1@_Sample_1           1    0.000249230    0.000249230    0.863    0.389
# A1@Treatments          5    0.232775       0.0465549    161.133    0.000
# A1@Residual_error      6    0.00173353     0.000288922     .        .
# A1@Total              11    0.234508       0.0213189       .        .
# P1@Potency             .  996.153       1029.95        1064.68      .
# P1@ReltoAss            .   99.6          103.0          106.5       .
# P1@ReltoEst            .   96.7          100.0          103.4       .
# C1@CommonSlope(factor) .    0.725012        .              .        .
# C1@Correlation|r|      .    0.995503        .              .        .
