Package: changeLOS
Version: 1.1.3
Title: Change in LOS
Author: Matthias Wangler <mw@imbi.uni-freiburg.de>, Jan Beyersmann <jan@fdm.uni-freiburg.de>
Maintainer: Matthias Wangler <mw@imbi.uni-freiburg.de>
Description: Change in length of hospital stay (LOS) is frequently used to assess the impact and the costs of hospital-acquired complications.
             In order to compute the attributable change in LOS, it is crucial to account for the timing of events:
             A complication can only have an effect on LOS, once it has occured. These temporal dynamics can be adequately handled by multistate models;
             however, there is few software for such models available.
             We introduce an R-package "changeLOS" for computing change in LOS based on methods described in Schulgen and Schumacher (1996).
             We will illustrate the program on data from a prospective cohort study on hospital-acquired infections.
             Main features of the R-package "changeLOS" are R-methods to: 
             (1) describe the multi-state model.
             (2) compute the Aalen-Johansen estimator for the matrix of transition probabilities P(u-, u) for all observed transition times u.
             (3) compute the Aalen-Johansen estimator for the matrix of transition probabilities P(s,t);
                 the estimator is a finite matrix product of matrices P(u-,u) for every observed event time in the interval(s,t]. 
             (4) visualize the temporal dynamics of the data, illustrated by transition probabilities. 
             (5) compute and visualize change in LOS.
             (6) compute bootstrap variances for change in LOS.
License: GPL (version 2 or later)
Packaged: Wed Feb 16 18:33:23 2005; mw
